Trasplante de microbiota fecal por colonoscopía en paciente mayor de 65 años con infección recurrente de Clostridioides difficile: aún una estrategia subutilizada

• Paulina Núñez ^[1] ; Rodrigo Quera ; Christian Von Muhlenbrock ; Alexandra Concha ; Katherine Flores
  1. [1] Universidad de Chile Facultad Medicina Occidente Hospital San Juan de Dios
• Localización: Revista Médica de Chile, ISSN-e 0034-9887, Vol. 150, Nº. 10, 2022, págs. 1396-1400
• Idioma: español
• Títulos paralelos:
  • Fecal microbiota transplantation in an older patient with Clostridioides difficile recurrent infection. Report of one case
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• Resumen

  • Clostridioides difficile infection (CDI) is a major public health problem and responsible for significant morbidity and mortality. Eighty percent of CDIs occur in adults older than 65 years of age due to a decreased gastrointestinal microbial diversity, immunosenescence and frailty. Thus, the most reported risk factor for recurrent CDI is older age since nearly 60% of cases occur in individuals aged ≥ 65 years. Fecal microbiota transplantation (FMT) is a highly cost-effective alternative to antibiotic treatment for patients with recurrent CDI. We report a 75-year-old male with recurrent CDI, who received a FMT after several unsuccessful antimicrobial treatments. He had a satisfactory evolution after the procedure and remained without diarrhea during the ensuing five months.