Synthesis of the ligand (z)-2-(3-methoxyphenylamino)-4-oxo-4-phenylbut-2-enoic acid and its antifungal activity against the wood stain fungi mucor plumbeus

C PAZ ^[1] ; D CAJAS-MADRIAGA ^[1] ; C TORRES ^[2] ; Y MORENO ^[1] ; M. J FERNÁNDEZ ^[1] ; J BECERRA ^[1] ; M SILVA ^[1]
1. [1] Universidad de Concepción
  
  Universidad de Concepción
  
  Comuna de Concepción, Chile
2. [2] Universidad del Biobío Departamento de Ciencias Naturales Laboratorio de Genómica y Biodiversidad
Localización: Journal of the Chilean Chemical Society (Boletín de la Sociedad Chilena de Química), ISSN-e 0717-6309, ISSN 0366-1644, Vol. 58, Nº. 2, 2013, págs. 1713-1716
Idioma: inglés
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Resumen
- The ligand (z)-2-(3-methoxyphenylamino)-4-oxo-4-phenylbut-2-enoic acid and its Ni (II) complex were synthesized and their antifungal activity against the fungi wood stain Mucor plumbeus was evaluated. The ligand displayed fungostatic activity while the Ni (II) complex exhibited antifungal activity with a MIC of 50 μg/mL, moreover the copper complex did not showed biocide activity.