Aristolochic acids in the roots of aristolochia chilensis, a dangerous chilean medicinal plant

• ALEJANDRO URZÚA ^[1] ; ANGEL OLGUÍN ^[1] ; ROCÍO SANTANDER ^[1]
  1. [1] University of Santiago de Chile Faculty of Chemistry and Biology Department of Environmental Sciences
• Localización: Journal of the Chilean Chemical Society (Boletín de la Sociedad Chilena de Química), ISSN-e 0717-6309, ISSN 0366-1644, Vol. 58, Nº. 4, 2013, págs. 2089-2091
• Idioma: inglés
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• Resumen

  • The chemical composition of aristolochic acids (AAs) from the roots of A. chilensis was determined by high-performance liquid chromatography with diode-array detection (HPLC-DAD), a technique widely used for the detection and quantification of AAs in herbal medicines. The roots contained a mixture of AA-I (1), AA-II (2), AA-III (3), AA-IV (4), AA-Ia (5), AA-IIIa (6), AA-IVa (7), and aristoloside (8), indicating that A. chilensis is not suitable for use as a medicinal plant due to the harmful effects of the aristolochic acids.