Como interpretar una revisión sistemática con comparaciones múltiples o network metaanálisis

• Autores: Gonzalo Labarca, Juan P. Uribe, Adnan Majid, Erik Folch, Sebastián Fernández Bussy
• Localización: Revista Médica de Chile, ISSN-e 0034-9887, Vol. 148, Nº. 1, 2020, págs. 109-117
• Idioma: español
• Títulos paralelos:
  • How to interpret systematic reviews with multiple comparisons or network meta-analysis
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• Resumen

  • Systematic reviews evaluating multiple interventions can be useful in different clinical situations. However, some concerns arise when more than two interventions are compared and there is a paucity of good quality randomized clinical trials. A novel statistical method based on indirect comparisons, called network meta-analysis (NMA), can be a useful approach to find a clinical answer when multiple interventions are evaluated for the same outcome or comparator. The aim of this review is to describe the main characteristics and provide a user guide for a critical analysis of NMA focusing on its three main domains, namely homogeneity, transitivity and consistency.