Resumen de Synthesis of 3 substituted isoquinolin-1-yl-2-(cycloalk-2-enylidene) hydrazines and their antimicrobial properties
P Manivel, S Mohana Roopan, R Sathish Kumar, F Nawaz Khan
New hydrazine derivatives were synthesized via reaction between 1, 3 cyclic diketones and hydrazinoisoquinohne derivatives. The reaction proceeded smoothly in ethanol under reflux temperature and furnished products in excellent yields (76-87%). The products have been purified and fully characterized by spectroscopy techniques. The compounds 8a-c showed good bacterial inhibition against Bacillus cerus and 8d-f showed good antifungal activity against Candida albicans.
