Synthesis of a-ring-substituted 5,6,8,12b-tetrahydroisoindolo[1,2-a]isoquinolin-8-ones

• VICENTE CASTRO-CASTILLO ^[1] ; MARCO REBOLLEDO-FUENTES ^[1] ; BRUCE K CASSELS ^[1]
  1. [1] Universidad de Chile

     Universidad de Chile

     Santiago, Chile

     
• Localización: Journal of the Chilean Chemical Society (Boletín de la Sociedad Chilena de Química), ISSN-e 0717-6309, ISSN 0366-1644, Vol. 54, Nº. 4, 2009, págs. 417-423
• Idioma: inglés
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• Resumen

  • The synthesis of 4,5,8,12b-tetrahydroisoindolo[1,2-a]isoquinolin-8-ones is reviewed The unsubstituted parent compound, a series of fourteen A-ring-substituted derivatives, most of them new, and some of their doubly benzylic, 12b-hydroxylated oxidation products were synthesized. Unusual features of their reactivity are briefy discussed.