Recurrencia de Síndrome de Goodpasture con negativización de anticuerpos anti-membrana basal glomerular: Caso clínico

• Autores: Rodrigo Tagle, Trinidad Arancibia, Alexandra Fischman, Sebastián Vázquez, Javier Chahuán, Gonzalo P. Méndez, Juan Pablo Huidobro E.
• Localización: Revista Médica de Chile, ISSN-e 0034-9887, Vol. 147, Nº. 3, 2019, págs. 390-394
• Idioma: español
• Títulos paralelos:
  • Recurrence of goodpasture syndrome with negative antiglomerular basement antibodies. Report of one case
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• Resumen

  • Goodpasture Syndrome is described as a single episode disease entity. It is diagnosed with the demonstration of antiglomerular basement (anti-GBM) antibodies in plasma or renal tissue. Although the recurrence of anti-GBM disease is rare, it has been reported in up to 3% of cases. Recurrence with negative anti-GBM antibodies in plasma is even less frequent We report a 63 years old male in whom anti-GBM disease recurred without detectable anti-GBM antibodies in plasma, despite having positive antibodies at the onset.