Antimicrobial activity of metabolites from mycelial cultures of chilean basidiomycetes

PEDRO AQUEVEQUE ^[1] ; JOSÉ BECERRA ^[1] ; GÖTZ PALFNER ^[1] ; MARIO SILVA ^[1] ; JULIO ALARCÓN ^[2] ; TIMM ANKE ^[4] ; OLOV STERNER ^[3]
1. [1] Universidad de Concepción
  
  Universidad de Concepción
  
  Comuna de Concepción, Chile
2. [2] Universidad del Bío-Bío
  
  Universidad del Bío-Bío
  
  Comuna de Concepción, Chile
3. [3] Lund University
  
  Lund University
  
  Suecia
4. [4] Universität, Paul-Ehrlich-Straße Lehrbereich Biotechnologie
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Localización: Journal of the Chilean Chemical Society (Boletín de la Sociedad Chilena de Química), ISSN-e 0717-6309, ISSN 0366-1644, Vol. 51, Nº. 4, 2006, págs. 1057-1060
Idioma: inglés
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Resumen
- We reported seven compounds isolated from mycelial cultures of Chilean Basidiomycetes. The compound structures were elucidated by spectroscopic methods. Two polyacetylenes were isolated from Gymnopilus spectabilis: hepta-4,6-diyn-3-ol(1) and 7-chloro-hepta-4,6-diyn-3 ol (2). We isolated the aromatic compounds p-anisaldehyde (3) and 3-chloro-p-anisaldehyde (4) from Hypholoma capnoides. H. fasciculare produced the compounds (3), (4),3,5-dichloro-4-metoxi-benzyl alcohol (5) and the sesquiterpen naematolon (6). Finally, H. sublateritiumproduced (5) and another sesquiterpen, marasmal (7). The compounds (1), (2), (5), and (7) showed biological activity against the tested model microorganism