Resumen de Regio and stereoselective hydroxylation of 5a-hydroxy-14-eudesm-11-en-3-one eudesmane by biotransformation of rhizopus nigricans

Sergio Águila, Julio Alarcón, Carolina Conejeros, Joel B Alderete

• This paper describes a combined synthesis of b-hydroxy-sesquiterpen eudesmane derivative using a microbiological hydroxylation sesquiterpen eudesmane derivative as the key reaction. The stereochemistry of the biohydroxylation was identified using mono and bi-dimensional ¹H-NMR experiments