Estudio comparativo de equipos INR capilar “point of care” versus INR venoso, en pacientes en tratamiento con antagonistas de vitamina K

• Autores: Ángela Roco, Elena Nieto, Marianela Quintana, Jessica Muñoz, Víctor Ortíz, Marcela Moreno, Fanny Mejía, Gerald Godoy, Johana Zambrano Salamanca, Stephanie Bruna, Gabriela Bravo, Claudia Cabrera, Patricio Salas, Valeria Moena, Bryan Leal, Marcelo Suárez, Luis A. Quiñones
• Localización: Revista Médica de Chile, ISSN-e 0034-9887, Vol. 147, Nº. 10, 2019, págs. 1273-1282
• Idioma: español
• Títulos paralelos:
  • Comparison of point of care capillary international normalized ratio (INR) with INR measured in venous samples
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• Resumen

  • Background: INR is used to monitor the treatment with vitamin K antagonists. A strategy to reduce waiting times for sampling is to measure INR in a capillary sample using a portable point of care (POC) type coagulometer. Aim: To evaluate the correlation of CoaguChek Pro II™, Xprecia™ and microINR™ with venous INR measured at the clinical laboratory and their ease of use. Materials and Methods: Patients provided capillary and venous blood samples for parallel tests comparing Xprecia™ Stride with CoaguChek Pro II™ and with venous INR, microINR™ with CoaguChek Pro IITM and with venous INR. The devices’ ease of use was assessed surveying the sampling staff. Results: The three tested devices had good correlation coefficients with venous INR: CoaguChek Pro IITM 0.953 and 0.962; Xprecia™ of 0.912 and microINR™ of 0.932. The correlation coefficient of Xprecia™ with CoaguChek Pro IITM was 0.937 and microINR™ with CoaguChek Pro IITM was 0.976. Conclusions: CoaguChek Pro IITM, Xprecia™ and microINR™ results had a good correlation coefficient with INR measured at the laboratory. Our results indicate that, in the hands of trained users, POC-type coagulometers are reliable and acceptable for routine use in anticoagulant treatment control.