Antiviral activity on hantavirus and apoptosis of vero cells of natural and semi-synthetic compounds from heliotropium filifolium resin

• B. Modak ^[1] ; H. Galeno ^[2] ; R. Torres ^[1]
  1. [1] Universidad de Santiago de Chile

     Universidad de Santiago de Chile

     Santiago, Chile

     
  2. [2] Instituto de Salud Pública de Chile Sección Virología
• Localización: Journal of the Chilean Chemical Society (Boletín de la Sociedad Chilena de Química), ISSN-e 0717-6309, ISSN 0366-1644, Vol. 49, Nº. 2, 2004, págs. 143-145
• Idioma: inglés
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• Resumen

  • The antiviral activity on Hantavirus Andes variety of resinous exudate from Heliotropim filifolium and its pure compounds was studied. From filifolinol 2, the main compound of the resins, filifolinoic acid 1 was obtained. The resin was the most active. Furthermore, we observed cytostatic effect and apoptosis on Vero E6 cells with 3-O-methylgalangine 5