Linfoma difuso de células grandes B rectal en un paciente con colitis ulcerosa

• Autores: Rodrigo Quera, Lilian Flores, Daniela Simian Marín, Udo Kronberg, María Teresa Vial, David Ladrón de Guevara H., María José García-Rodríguez
• Localización: Revista Médica de Chile, ISSN-e 0034-9887, Vol. 145, Nº. 10, 2017, págs. 1342-1348
• Idioma: español
• Títulos paralelos:
  • Rectal diffuse large B cell lymphoma appearing after immunosuppression for ulcerative colitis. Report of one case
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• Resumen

  • Primary colorectal lymphoma is a rare form of presentation of gastrointestinal tract lymphomas. Inflammatory bowel disease and its treatment are risk factors for its development. We report a 47-year-old male patient with Ulcerative Colitis of two years of evolution, treated initially with azathioprine and later on with infliximab. Due to a relapse in symptoms after the second dose of infliximab, a new coloncoscopy was performed showing a rectal ulcerative lesion, corresponding to a large cell Non-Hodgkin's Lymphoma. The patient was successfully treated with RCHOP chemotherapy (Rituximab cyclophosphamide doxorubicin vincristine prednisone). He is currently in disease remission.