Infección por virus respiratorios en adultos hospitalizados en un Servicio de Medicina Interna

• Raúl Riquelme ^[2] ; María Luisa Rioseco ^[1] ; Yasna Agüero ^[2] ; Daniela Ubilla ^[2] ; Pamela Mechsner ^[2] ; Carlos Inzunza ^[2] ; Mauricio Riquelme ^[2]
  1. [1] Universidad San Sebastián

     Universidad San Sebastián

     Comuna de Concepción, Chile

     
  2. [2] Hospital de Puerto Montt Servicio de Medicina Interna
• Localización: Revista Médica de Chile, ISSN-e 0034-9887, Vol. 142, Nº. 6, 2014, págs. 696-701
• Idioma: español
• Títulos paralelos:
  • Respiratory virus infections in adult patients hospitalized in an internal medicine unit
• Enlaces
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• Resumen

  • Background: Respiratory viral infections (RVi) can be associated with a wide range of clinical manifestations. Aim: To investigate the frequency and clinical manifestations of RVi among adult patients during winter hospitalizations. Patients and Methods: All patients admitted to the hospital with flu like disease and those with fever or exacerbation of any underlying disease during hospitalization without an evident cause, were prospectively enrolled. A direct immunofluorescence (DIF) of nasopharyngeal aspirate for influenza A (IA) and B, parainfluenza 1, 2 and 3, adenovirus, respiratory syncytial virus (RSV) and metapneumovirus, was performed. Epidemiological and clinical data were recorded. Results: Between May and September 2012, 975 adults were admitted to the Internal Medicine Unit of Puerto Montt Hospital and in 128 (13%) patients, DIF was carried out. DIF was positive in 44 patients (34%) aged 65 ± 20 years, 68.2% females, corresponding to 4.5% of total hospitalizations. Eighty six percent of the latter had at least one co-morbidity, mainly asthma and chronic respiratory diseases in 34.1%, diabetes in 29.5%, cardiac problems in 25% and congestive heart failure in 20.5%. The most common RVi were RSV (n = 21, 48%) and IA (n = 17, 39%). Six patients had a nosocomial RVi. Patients infected with IA had a significantly higher frequency of fever and bronchial hyper reactivity than those infected with RSV. RVi were associated with exacerbation of underlying disease in 62% of cases and pneumonia in 27%. Two patients had a viral pericarditis. Conclusions: RVi are an important cause of adult morbidity and their detection should be routine in adult patients hospitalized during winter.