Compromiso multisistémico en apnea obstructiva del sueño

• Gonzalo Labarca ^[1] ; Rodrigo Cruz N ^[2] ; Fernando Descalzi ^[1]
  1. [1] Universidad del Desarrollo

     Universidad del Desarrollo

     Santiago, Chile

     
  2. [2] Universidad de Valparaíso

     Universidad de Valparaíso

     Valparaíso, Chile

     
• Localización: Revista Médica de Chile, ISSN-e 0034-9887, Vol. 142, Nº. 6, 2014, págs. 748-757
• Idioma: español
• Títulos paralelos:
  • Multisystemic involvement in obstructive sleep apnea
• Enlaces
  • Texto completo
• Resumen

  • Obstructive Sleep Apnea (OSA) is characterized by repetitive upper airway collapse with apnea/hypopnea and recurrent hypoxia during sleep, which results in fragmented sleep and intermittent drops in arterial blood oxygen saturation (hypoxemia). Several dysfunctions of neurocognitive, endocrine, cardiovascular, and metabolic systems are recognized in patients with OSA. The most commonly reported associations are with obesity, increased cardiovascular risk, dyslipidemia, diabetes mellitus 2 and liver damage. However, there is a proven relationship between OSA and other diseases, such as polycystic ovary syndrome, gastroesophageal reflux, and chronic kidney disease. The aim of this review is to analyze clinical and experimental evidence linking OSA with other diseases.