Hemangioendotelioma epitelioide y fusiforme de ganglio linfático: Caso clínico

• Alejandro Avilés-Salas ^[2] ; José Cruz Torres-Lucatero ^[2] ; Ximena Fernandez-Soto ^[1] ; Myrna Candelaria-Hernández ^[3]
  1. [1] Universidad Nacional Autónoma de México

     Universidad Nacional Autónoma de México

     México

     
  2. [2] Instituto Nacional de Cancerología Departamento de Patología
  3. [3] Instituto Nacional de Cancerología Departamento de Hematología

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• Localización: Revista Médica de Chile, ISSN-e 0034-9887, Vol. 141, Nº. 2, 2013, págs. 260-263
• Idioma: español
• Títulos paralelos:
  • Spindle and epithelioid hemangio-endothelioma of the lymph node: Report of one case
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• Resumen

  • Background: Primary vascular tumors of lymph nodes are extremely rare with the exception of AlDS-related Kaposi's sarcoma. The diagnosis of epithelioid hemangio-endothelioma (EH) is difficult to make without ancillary studies, since it is devoid of morphological features indicating its vascular nature and it may be overlooked when it appears as a primary tumor of lymph nodes. Spindle and epithelioid hemangio-endothelioma (SEH) is considered to be a variant of EH, which has been reported to occur exclusively in lymph nodes and the spleen. We report a 70-year-old male with chronic lymphocytic leukemia (CLL) and left cervical lymphadenopathy. An excisional biopsy was performed, and microscopically the lymph node showed effacement of nodal architecture by a tumor composed of spindle cells disposed in intersecting fascicles, and characterized by abundant eosinophilic cytoplasm, elongated nuclei and conspicuous nucleoli. A second population of cells had an epithelioid appearance with intracyto-plasmic vacuoles containing red blood cells. lmmunohistochemically, the tumor cells were positive for CD31 and CD34. The final diagnosis was SEH of the lymph node.