Vasculitis primaria del sistema nervioso central, diagnóstico diferencial de demencia subaguda: Caso clínico

• Pablo Araya C ^[1] ; Claudio Sacks P ^[2] ; Paula Muñoz V ^[2] ; Juan Pablo Gigoux L ^[1] ; Luis García F ^[1] ; Gonzalo Matamala H ^[1] ; Juan Idiáquez C ^[2]
  1. [1] Hospital Naval Almirante Nef

     Hospital Naval Almirante Nef

     Viña del Mar, Chile

     
  2. [2] Universidad de Valparaíso

     Universidad de Valparaíso

     Valparaíso, Chile

     
• Localización: Revista Médica de Chile, ISSN-e 0034-9887, Vol. 137, Nº. 6, 2009, págs. 807-810
• Idioma: español
• Títulos paralelos:
  • Primary vasculitis of the Central Nervous System: Report of one case
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• Resumen

  • A primary central nervous system vaculitis is an uncommon and invalidating disease, which has a fatal course if left untreated. We report a 63 year-old woman presenting with a history of two months of cognitive impairment, dysarthria, gait instability and tremor. After four months of evolution a right hemianopsia and a flaccid paresis of upper right limb appeared. A brain biopsy was performed and the histological findings confirmed the suspicion of primary cerebral vasculitis. The patient was treated with cyclophosphamide and prednisone, observing a partial recovery of cognitive and motor function.