Radiosurgery in glioblastoma: A literature review

• Autores: Jose E Valerio, Maria Paula Fernandez Gomez, Noe Santiago, Andrés M. Álvarez
• Localización: Revista Med de la Facultad de Medicina, ISSN 0121-5256, ISSN-e 1909-7700, Vol. 31, Nº. 2, 2023, págs. 71-78
• Idioma: inglés
• Títulos paralelos:
  • Radiocirugía en glioblastoma: una revisión de la literatura
• Enlaces
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• Resumen

  • Managing high-grade gliomas, particularly glioblastoma, remains challenging despite advancements in radiation therapy and surgery. The standard care involves maximal surgical resection, followed by radiotherapy and Temozolomide chemotherapy. Gamma Knife Stereotactic Radiosurgery (GKRS) has emerged as a noninvasive and effective option for treating a range of central nervous system lesions. GKRS offers precise, low-energy radiation delivery to a defined target, inducing tissue destruction while sparing healthy brain tissue. Although, side effects such as radiation necrosis have been noted, GKRS shows promise in treating glioblastoma, even with its infiltrative nature. This review explores the evolving landscape of high-grade glioma manage-ment, focusing on the potential of GKRS in improving treatment outcomes