Utilidad de la deoxiglucosa marcada con flúor-18 (FDG) en el manejo de los linfomas

• Teresa Massardo V ^[1] ; José Canessa G ^[2] ; M Josefina Jofré M ^[2] ; Patricio González E ^[1] ; Pamela Humeres A ^[3] ; Paulina Sierralta G ^[2]
  1. [1] Universidad de Chile

     Universidad de Chile

     Santiago, Chile

     
  2. [2] Hospital Militar de Santiago

     Hospital Militar de Santiago

     Santiago, Chile

     
  3. [3] Clinica Santa Maria

     Clinica Santa Maria

     Santiago, Chile

     

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• Localización: Revista Médica de Chile, ISSN-e 0034-9887, Vol. 134, Nº. 7, 2006, págs. 910-919
• Idioma: español
• Títulos paralelos:
  • Role of 18Fluorine-deoxyglucose (FDG) positron emission tomography in the management of lymphomas
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• Resumen

  • Positron emission tomography (PET) with fluorine-18 labeled deoxyglucose (FDG) is useful in the management of lymphomas. In this review, some general concepts of this metabolic test are defined. It has an excellent diagnostic yield in Hodgkin disease as well as in most non Hodgkin lymphomas. Staging, restaging residual mass evaluation and the control of therapy are the main indications for FDG-PET. Images with FDG have a high diagnostic and prognostic value, that is superior to anatomical images and conventional staging techniques. They are also helpful for the assessment of tumor activity in abnormal lymph nodes or large masses that have been treated and reduce their size slowly or show an incomplete resolution. Currently, the resolution of dedicated PET equipments is 6 mm and bigger lesions can easily be detected. The main differences and advantages of FDG versus gallium-67 in lymphoma are also discussed, as well as the initial local experience with the technique in lymphoma patients