Alta prevalencia de síndrome de Down en el Hospital Regional Rancagua, Chile: Período 1997-2003

• María Elena Ojeda B ^[1] ; Rodrigo Moreno S ^[1]
  1. [1] Servicio de Salud Libertador Bernardo O'Higgins Hospital Regional de Rancagua
• Localización: Revista Médica de Chile, ISSN-e 0034-9887, Vol. 133, Nº. 8, 2005, págs. 935-942
• Idioma: español
• Títulos paralelos:
  • High prevalence of Down syndrome in the Rancagua Hospital in central Chile
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• Resumen

  • Background: The Latin American Collaborative Study for Congenital Malformations (ECLAMC) has detected a higher incidence of Down syndrome in a zone of central Chile than in the rest of the country. Aim: To analyze the incidence rates of Down syndrome between 1997 and 2003 at the Regional Hospital of Rancagua, located 90 km south of Santiago, Chile. Material and methods: The information obtained by ECLAMC was used. This program, using a case control methodology, registers all newborns with congenital malformations and assigns, as a control, the next normal newborn of the same sex. Results: During the study period, 106 newborns with Down syndrome were registered, with a mean rate of 29.61 per 10,000 live births, twice higher than expected. The rate variations along the years of study suggest a cyclic change, with a hemicycle of six years. Conclusions: In this hospital, mothers under 35 years of age, have twice the risk of having a child with Down syndrome, than in the rest of the country