Estudio de sensibilidad in vitro de cepas de Streptococcus pneumoniæ de infecciones respiratorias bajas en el Instituto Nacional del Tórax (INT)

• Tamara Soler V ^[1] ; Lucía Salamanca F ; Guillermo Arbo OM ; Eliana Molina E
  1. [1] Instituto Nacional del Tórax Servicio de Medicina
• Localización: Revista Médica de Chile, ISSN-e 0034-9887, Vol. 130, Nº. 3, 2002, págs. 304-308
• Idioma: español
• Títulos paralelos:
  • In vitro susceptibility of Streptococcus pneumoniæ strains isolated from lower respiratory infections
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• Resumen

  • Background: The rising antimicrobial resistance of streptococcus pneumoniæ, requires permanent surveillance. Antimicrobial treatments of invasive infections must be modified accordingly. Aim: To assess the in vitro antimicrobial susceptibility of streptococcus pneumoniæ strains isolated from lower respiratory infections. Material and methods: Seventy five strains isolated during three periods in consecutive years were studied. In vitro susceptibility towards penicillin, erythromycin and ceftriaxone was studied using E-test technique minimal inhibitory concentrations. Results: Five percent of strains were penicillin resistant and 11% had an intermediate sensitivity. Erythromycin resistance was observed in 1.3% of strains. Eight percent of strains had an intermediate sensitivity towards ceftriaxone and no resistance was observed. Comparing susceptibility in the three studied periods, it remained low and stable. Conclusions: High and intermediate resistance of Strepfococcus pneumoniæ towards penicillin is less prevalent than in other countries. A close surveillance must be maintained (Rev Méd Chile 2002; 130: 304-8)