Cambios en los patrones de prescripción de medicamentos en el infarto agudo del miocardio.: Comparación de dos períodos

• Juan Carlos Prieto D ^[1] ; Ramón Corbalán H ; Carolina Nazza N ; Eduardo Chávez S ; Fernando Lanas Z ; Jorge Bartolucci J ; Francisco Cumsille G
  1. [1] Universidad de Chile Facultad de Medicina Hospital Clínico Universidad de Chile
• Localización: Revista Médica de Chile, ISSN-e 0034-9887, Vol. 129, Nº. 5, 2001, págs. 481-488
• Idioma: español
• Títulos paralelos:
  • Changes in pharmacotherapy for acute myocardial infarction: Comparison of two periods
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• Resumen

  • Background: Pharmacotherapy of Chilean patients with acute myocardial infarction has been recorded in 37 hospitals since 1993. Aim: to compare pharmacotherapy for acute myocardial infarction in the period 1993 to 1995 with the period 1997-1998. Patients and methods: Drug prescription during hospital stay was recorded in 2957 patients admitted to Chilean hospitals with an acute myocardial infarction in the period 1993-1995 and compared with that of 1981 subjects admitted in the period 1997-1998. Results: When compared with the former period, in the lapse 1997-1998 there was an increase in the frequency of prescription of aspirin (93 and 96.1% respectively) ß blockers (37 and 55.2% respectively) and angiotensin converting enzyme inhibitors (32 and 53%). The prescription of thrombolytic therapy did not change (33 and 33.7% respectively). There was a reduction in the prescription of calcium antagonists and antiarrhythmic drugs. Conclusions: During the period 1997-1998, the prescription of drugs with a potential to reduce the mortality of acute myocardial infarction, increased. The diffusion of guidelines for the management of this disease may have influenced this change. (Rev Med Chile 2001; 129: 481-8)