The win ratio is a statistical method most commonly used for ana- lyzing composite outcomes in clinical trials. Composite outcomes comprise two or more distinct “component” events (for example, myocardial infarction or death) and are typically analyzed using time-to-first-event methods ignoring the relative importance of the component events. When using the win ratio, component events are instead placed into a hierarchy from most to least important; more important components can then be prioritized over less important outcomes (for example, death can be prioritized over myocardial infarction). Furthermore, the win ra- tio enables outcomes of different types (for example, time-to-event, continuous, binary, ordinal, and repeat events) to be combined. We present winratiotest, a command to implement the win-ratio approach for hierarchical outcomes in a flexible and user-friendly way.
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