Resumen de Phase angle and other vectors of bioelectrical impedance behavior and its relations with metabolism markers of eccentric muscle damage after ischemic preconditioning:: Randomized placebo-controlled clinical trial
Julia Waszczuk Vendrame, Eduardo Pizzo Junior, Allysiê Priscilla de Souza Cavina, Carlos Alberto Toledo Teixeira Filho, Taíse Mendes Biral, Gabriel Martins da Silva, Renan Alves Matsumoto, Guilherme Henrique da Silva Brandão, Franciele Marques Vanderlei
Background/Objective:Eccentric Exercise (EE) can induce muscle damage, but ischemic pre-conditioning (IPC) emerge as a valuable approach to hasten the recovery process. Monitoringserum markers of muscle damage and assessing cellular health are essential to evaluate theeffectiveness of this approach. Therefore, this study aimed to evaluate the behavior of cellularresponses through bioelectrical impedance (BIA) vectors after IPC at different occlusion pres-sures and correlate them with indirect markers of eccentric muscle damage as creatine kinase(CK) and lactate dehydrogenase (LDH).Methods:Eighty men were divided into four groups: IPC with arterial occlusion pressure (AOP),IPC with 40 % above AOP, placebo, and control. All groups underwent an EE protocol and wereevaluated for CK, LDH, and BIA. Repeated measures analysis of variance was used, and correla-tions were performed using Pearson or Spearman correlation depending on data normality. Thesignificance level was set atp<0.05.Results:The placebo and control groups showed an increase in CK and LDH levels, along with adecrease in cellular integrity. The IPC-AOP group exhibited an increase in CK and LDH levels, butwithout negative impact on resistance, integrity, and cellular health. The IPC-40 % group showed an increase in CK, decrease in cellular health, elevation of LDH, and higher tissue electricalresistance.Conclusion:The interventions were not effective in maintaining cellular health in the context ofeccentric muscle damage.
