Synthesis of novel lipoic acid derivatives

• González-Gutiérrez, Juan Pablo ^[1] ; Moris, Silvana ^[2] ; Barrientos, Claudio ^[2]
  1. [1] Universidad Autónoma de Chile

     Universidad Autónoma de Chile

     Temuco, Chile

     
  2. [2] Universidad Católica del Maule

     Universidad Católica del Maule

     Provincia de Talca, Chile

     
• Localización: Journal of the Chilean Chemical Society (Boletín de la Sociedad Chilena de Química), ISSN-e 0717-6309, ISSN 0366-1644, Vol. 69, Nº. 1, 2024 (Ejemplar dedicado a: JCChemS), págs. 6054-6055
• Idioma: inglés
• Enlaces
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• Resumen

  • Lipoic acid is a naturally occurring compound involved in biological processes with special reactivity due to its 1,2-dithiolane ring. The novel ALA derivatives were synthesized using the Steglich esterification in mild conditions and then concentrated and neutralized with yields of 45.1 to 81.2%.