Conundrums of Diagnosis and Management of Cushing’s Syndrome in Pregnancy

• Livia Gheorghiu, Monica ^[2] ; Fleseriu, Maria ^[1]
  1. [1] Oregon Health & Science University

     Oregon Health & Science University

     Estados Unidos

     
  2. [2] Department of Clinical Endocrinology IV, Carol Davila University of Medicine and Pharmacy Bucharest, Romania; b CI Parhon National Institute of Endocrinology, 34-36 Aviatorilor Boulevard, Sector 1, 011863, Bucharest, Romania;
• Localización: Endocrinology and metabolism clinics of North America, ISSN 0889-8529, Vol. 53, Nº. 2, 2024, págs. 421-435
• Idioma: inglés
• Enlaces
  • Texto completo
• Resumen

  • Pregnancy is rare in women with CS, but active CS poses many risks for both mother and fetus, and women should be managed by an expert multidisciplinary team. A diagnosis is challenging due to the overlap with clinical and biochemical changes that occur in normal pregnancies. All biochemical tests have potential pitfalls and furthermore, normal ranges differ from those outside pregnancy. The first line of treatment is surgery (preferably in the second trimester). In severe cases, medical