Genetic and cytological characterization of a developmental mutant of Aspergillus nidulans induced by 5-azacytidine

MARCO ANTONIO COSTA ^[1] ; NELMARA CRISTINA GONÇALVES SILVA ^[2] ; MARIALBA AVEZUM ALVES CASTRO-PRADO ^[2]
1. [1] Universidade Paranaense
  
  Universidade Paranaense
  
  Brasil
2. [2] Universidade Estadual de Maringá
  
  Universidade Estadual de Maringá
  
  Brasil
Localización: Biological Research, ISSN-e 0717-6287, ISSN 0716-9760, Vol. 34, Nº. 2, 2001, págs. 91-98
Idioma: inglés
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Resumen
- An analysis of a new medusa mutant of Aspergillus nidulans obtained by 5-azacytidine-treatment and named B116 is provided. The B116 mutant was phenotypically characterized by the production of conidiophores with reduced pigmentation and vesicles bearing multiple tiers of sterigmata. A single nuclear gene located on chromosome I is responsible for phenotypical changes in the mutant. The 5-azacytidine-altered locus, designated medA102, is recessive in heterozygous diploid and the medusa mutant is a Dp(II,I) duplication bearer that renders the strain mitotically unstable.