In vitro approach to the chemical drive of breathing

• JAIME EUGENIN ^[1] ; ISABEL LLONA ; CLAUDIA D INFANTE ; ESTIBALIZ AMPUERO
  1. [1] Universidad de Santiago de Chile

     Universidad de Santiago de Chile

     Santiago, Chile

     
• Localización: Biological Research, ISSN-e 0717-6287, ISSN 0716-9760, Vol. 34, Nº. 2, 2001, págs. 117-122
• Idioma: inglés
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• Resumen

  • Since its introduction two decades ago, the isolated brain stem-spinal cord preparation of neonatal rodents has been the preferred method used to reveal the mystery underlying the genesis of the respiratory rhythm. Little research using this in vitro approach has focused on the study of the central respiratory chemosensitivity. Some unexpected findings obtained with the brain stem-spinal cord preparation have added new questions that challenge our previous theoretic framework. Some of these findings are addressed here.