Introduction: Acute myocardial infarction (AMI) is a manifestation of coronary artery disease, a determinant of mortality for men and women in the fifth decade of life. Objective: To identify the differences in diagnostic and therapeutic tests according to sex in patients with ST-elevation myocardial infarction. Methods: quantitative, cross-sectional, retrospective investigation in 155 patients, 97 men and 58 women, admitted to Coronary Intensive Care, Institute of Cardiology and Cardiovascular Surgery with ST-segment elevation myocardial infarction, January 2020-December 2021. Variables related to diagnosis and treatment were explored. Results: on admission, more than 55% of the patients attended underwent reperfusion treatment, which was a very effective therapy in all cases. Women were more often reperfused by PCI (50 %) and men by thrombolysis (15.5 %). During hospitalization, 77.32 % of men required a second PCI and 52.6 % a PTCA, while 65.52 % of women and 43.10 % of men required a second PCI and 52.6 % a PTCA. 67.7 % (130 cases) with transthoracic ECHO performed were normal, the more severe degrees of involvement of the left ventricular ejection fraction was decreased. Conclusions: There were diagnostic and therapeutic differences according to sex. The left ventricular ejection fraction was more affected in men and a greater number of altered complements. It is necessary to improve the early identification and management of women with ST-segment elevation myocardial infarction
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