Introduction: premalignant lesions may appear in the oral cavity, to which we must be alert, to facilitate the early diagnosis of oral cancer. Leukoplakia is a white, premalignant lesion that does not come off when scraped and cannot be classified as another disease. Objective: to present a case of homogeneous oral leukoplakia on a middle rhomboidal glossitis. Case presentation: a 49-year-old patient is presented, with a health history, who attended a dental consultation for periodic check-ups, in whom a whitish lesion was detected on the dorsal surface of the tongue. During the interrogation, the patient's oral habit was: cheilophagia and a history of burn trauma in the referred area. Once referred to the Maxillofacial Surgery service, the lesion was excised and biopsied, corresponding to homogeneous leukoplakia. Medial rhomboid glossitis and a history of burn trauma are assumed to be risk factors. Conclusions: the evolution was favorable for one year. Early diagnosis and consequent treatment were possible, contributing to the early detection and prevention of a cancerous lesion.
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