Design and synthesis of novel bio-nanohybrid materials: catalytic applications in reactions of interest to the fine-chemical/pharmaceutical industries
- Autores: Ronald Alexander Miranda Acevedo
- Directores de la Tesis: Jesús Eduardo Sueiras Romero (dir. tes.), Anna Maria Segarra González (dir. tes.)
- Lectura: En la Universitat Rovira i Virgili ( España ) en 2012
- Idioma: inglés
- Tribunal Calificador de la Tesis: Eduardo Ruiz-Hitzky (presid.), José María Fraile Dolado (secret.), M. Rosa Axet Martí (voc.)
- Materias:
- Enlaces
- Tesis en acceso abierto en: TDX
- Resumen
Bio-nanohybrid materials based on the combination of biomolecules and inorganic supports are interesting by their versatile applications in regenerative medicine, drug delivery, bio-engineering and catalysis. In that context, understanding of organic/inorganic interactions offers an important key to design new and more complex bio-systems with modified interactions. In this thesis, amino acids and synthesised poly-amino acids were immobilised in hydrotalcite-like materials under green, controllable and efficient protocols. Additionally, these nanohybrid materials were used as heterogenized catalysts exhibiting high catalytic activity and selectivity in comparison with their counterpart components. All result data showed that the location and nature of the immobilization had an important role in the final chemical properties; moreover, this novel bio-nanohybrid material exhibited excellent synergistic behaviour which was unique for each material and could be modified according with the reaction requirements. All novel bio-nanohybrid materials were easily synthesised, recovered and, in some cases, reused without appreciable deactivation.
