Vascular catheters are the most used medical devices in healthcare settings. For the last decade,catheter related bloodstream infections (CRBSIs) have been a major threat to patient’s safety.In Bellvitge University Hospital (BUH), a bundle of intervention was applied sequentialy from 2003 to 2016 to decrease the rate of CRBSIs.This research work highlights the epidemiology of the peripheral catheter- related bloodstream infections (PVCR-BSI) throughout this study period following the application of the bundle and from the other side it reflects on the risk factors associated with mortality among these episodes of CRBSIs. In conclusion, this PhD thesis work ,demonstrates the effectiveness of the application of the multimodal prevention program in BUH in terms of reducing CRBSIs, and emphasize that Staphylococcus aureus and the Candida infections and a comorbidity index of Charlson score > 4,are independent risk factors for mortality among patients with CRBSIs.
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