EMBO journal: European Molecular Biology Organization

• 

  Año 2012, Vol. 31, Número 10

  • Article

    • The mechanism of γ-Secretase dysfunction in familial Alzheimer disease

      Lucía Chávez Gutiérrez, Leen Bammens, Iryna Benilova, Annelies Vandersteen, Manasi Benurwar, Marianne Borgers, Sam Lismont, Lujia Zhou, Simon van Cleynenbreugel, Hermann Esselmann, Jens Wiltfang, Lutgarde Serneels, Eric Karran, Harrie Gijsen, Joost Schymkowitz, Frederic Rousseau, Kerensa Broersen, Bart De Strooper

      • Resumen
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      págs. 2261-2274

      

    • Novel repressor regulates insulin sensitivity through interaction with Foxo1

      Jun Nakae, Yongheng Cao, Fumihiko Hakuno, Hiroshi Takemori, Yoshinaga Kawano, Risa Sekioka, Takaya Abe, Hiroshi Kiyonari, Yoshiya Tanaka, Juro Sakai, Shin-Ichiro Takahashi, Hiroshi Itoh

      • Resumen
      • Texto completo

      págs. 2275-2295

      

    • Disabled-2 (Dab2) inhibits Wnt/β-catenin signalling by binding LRP6 and promoting its internalization through clathrin

      Yong Jiang, Xi He, Philip H. Howe

      • Resumen
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      págs. 2336-2349

      

    • Oligomers of the ATPase EHD2 confine caveolae to the plasma membrane through association with actin

      Miriam Stoeber, Ina Karen Stoeck, Christine Hänni, Christopher D. Black, Giuseppe Balistreri, Ari Helenius

      • Resumen
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      págs. 2350-2364

      

    • The location of splenic NKT cells favours their rapid activation by blood-borne antigen

      Patricia Barral, M. Dolores Sánchez Niño, Nico van Rooijen, Vincenzo Cerundolo, Facundo D. Batista

      • Resumen
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      págs. 2378-2390

      

    • Breaking the HAC Barrier: Histone H3K9 acetyl/methyl balance regulates CENP-A assembly

      Jun-ichirou Ohzeki, Jan H. Bergmann, Natalay Kouprina, Vladimir N. Noskov, Megumi Nakano, Hiroshi Kimura, William C. Earnshaw, Vladimir Larionov, Hiroshi Masumoto

      • Resumen
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      págs. 2391-2402