Illustrating Catalysis with Interlocking Building Blocks: A BINAP-Ruthenium Complex Catalyzed Asymmetric Hydrogenation

• Autores: Ryo Horikoshi
• Localización: Journal of chemical education, ISSN 0021-9584, Vol. 92, Nº 2, 2015, págs. 332-335
• Idioma: inglés
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• Resumen

  • A unique method has been developed using an interlocking building-block model equipped with magnets to illustrate the catalytic asymmetric hydrogenation of ß-keto esters by a BINAP-ruthenium complex to enhance students' understanding of this process. A BINAP-ruthenium block model, mimicking the coordination environment around the metal center in the real complex, can be used to convert the ß-keto ester model into a ß-hydroxy ester model. This model was used to provide a greater understanding of the essence of the catalytic reaction and to assist students in their understanding of its mechanism.