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Resumen de NAIP inflammasomes give the NOD to bacterial ligands

Vivien I. Maltez, Edward A. Miao

  • NLRs are innate immune sensors that monitor the sanctity of the cytosolic compartment. In a recent paper in Molecular Cell, Tenthorey et al. reveal a novel ligand-sensing interface within regions of the oligomerization domain of the NAIPs, rather than within the leucine-rich repeats, as was anticipated.


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