An easy and fast experiment for the determination of the equilibrium constants of an acid-base pair, free and complexed with a molecular receptor.

• Elena Junquera ^[1] ; Emilio Aicart ^[1]
  1. [1] Universidad Complutense de Madrid

     Universidad Complutense de Madrid

     Madrid, España

     
• Localización: Journal of chemical education, ISSN 0021-9584, Vol. 77, Nº 9 (September), 2000, págs. 1215-1215
• Idioma: inglés
• Texto completo no disponible (Saber más ...)
• Resumen

  • This paper shows a pH-potentiometric technique, an experimental procedure, and a mathematical model, easily affordable in the laboratory, for the simultaneous and fast determination of all the equilibrium constants involved in the competitive association of an acid-base pair substrate with a molecular receptor in aqueous solution. From the dependence of these association constants on temperature (van't Hoff analysis), the change of the enthalpy, ΔH°, and the entropy, ΔS°, of the processes can be estimated and discussed in terms of the driving forces governing the interactions.