Wine and the effect of body weight on Ethyl carbamate‐induced tumorigenesis in mice

• Gilbert S. Stoewsand ^[1] ; Judy L. Anderson ^[1] ; Linda Munson ^[2]
  1. [1] Cornell University

     Cornell University

     City of Ithaca, Estados Unidos

     
  2. [2] University of Tennessee
• Localización: Journal of wine research, ISSN 0957-1264, Vol. 7, Nº 3, 1996, págs. 207-211
• Idioma: inglés
• Texto completo no disponible (Saber más ...)
• Resumen

  • Ethyl carbamate (EC; urethane), a known carcinogen, can be naturally present in small amounts within fermented foods, including wine. Growing male, C3H mice fed EC in wine for 41 weeks showed a lower frequency of EC‐induced tumours in their livers and lungs than mice receiving the same level of EC in water. From comparable tumour development in mice fed restricted amounts of ethanol or water, it appeared that the ethanol in wine as well as lowered food intake with lowered body weights in the wine‐treated animals were responsible for reducing EC‐induced tumour frequency.