Ludovic Sauguet, Frédéric Poitevin, Samuel Murail, Catherine van Renterghem, Gustavo Moraga Cid, Laurie Malherbe, Andrew W. Thompson, Patrice Koehl, Pierre-Jean Corringer, Marc Baaden, Marc Delarue
The high-resolution crystal structure of a pentameric ligand-gated ion channel reveals that hydroxylated residues and two water pentagon rings form an ion selectivity filter, explaining ion transport across hydrophobic constriction barriers.
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