Development of a Large-Enrollment Course-Based Research Experience in an Undergraduate Organic Chemistry Laboratory: Structure–Function Relationships in Pyrylium Photoredox Catalysts

• Cole L. Cruz ^[1] ; Natalie Holmberg-Douglas ^[1] ; Nicholas P. R. Onuska ^[1] ; Joshua B. McManus ^[1] ; Ian A. MacKenzie ^[1] ; Bryant L. Hutson ^[1] ; Nita A. Eskew ^[1] ; David A. Nicewicz ^[1]
  1. [1] University of North Carolina—Chapel Hill, United States
• Localización: Journal of chemical education, ISSN 0021-9584, Vol. 97, Nº 6, 2020, págs. 1572-1578
• Idioma: inglés
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• Resumen

  • Despite the recognized effectiveness of course-based undergraduate research experiences (CUREs), there are few examples of the development of a CURE-based course in a large-enrollment undergraduate organic chemistry laboratory. Herein, we describe the development and implementation of a series of undergraduate laboratory experiments centered around the synthesis and characterization of pyrylium salts in the context of photoredox catalysis. Pre- and post-survey data regarding the CURE features of collaboration, discovery, iteration, and student project ownership also highlight the strengths of the CURE implementation in this large-scale lab course.