Stu2p and XMAP215: turncoat microtubule-associated proteins?

• Autores: Eric Karsenti, Andrei V. Popov
• Localización: Trends in cell biology, ISSN 0962-8924, Vol. 13, Nº. 11 (November), 2003, págs. 547-549
• Idioma: inglés
• Texto completo no disponible (Saber más ...)
• Resumen

  • The dynamics of microtubule-based (MT) cytoskeletons are controlled by a variety of accessory proteins: microtubule-associated proteins (MAPs), which usually stabilize MTs, and microtubule-destabilizers. Two related MAPs, XMAP215 and Stu2p, are known to stabilize MTs. However, recent studies report that these proteins have a MT-destabilizing function as well. Here we discuss the implications of these reports.