Synthesis and Biological Assay of Small-Molecule Quorum Sensing Inhibitors: A Three-Week Course-Based Undergraduate Research Experience

• Stanna K. Dorn ^[1] ; Jane D. Newman ^[1] ; Julia C. van Kessel ^[1] ; Laura C. Brown ^[1]
  1. [1] Indiana University, United States
• Localización: Journal of chemical education, ISSN 0021-9584, Vol. 98, Nº 11, 2021, págs. 3533-3541
• Idioma: inglés
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• Resumen

  • We have developed a course-based undergraduate research experience (CURE) that can be carried out in the context of an existing second-semester or upper-level organic laboratory course. In this three-week laboratory module, students synthesize a small library of molecules, test them in a robust biological assay, and design a new compound library on the basis of their results.