Resumen de Advances in total synthesis of alternaric acid: An anti-fungal and phytotoxic natural product
Sajjad Ahmad, Muhammad N. Yousaf, Ameer Fawad Zahoor, Matloob Ahmad, Zulfiqar Ali Khan, Mohammad Rashid
Alternaric acid is characterized as 1,4-diene, possessing (E)-1,2-disubstituted alkene known for nanomolar phytotoxic and antifungal activities. This article highlights the major synthetic approaches attempted towards the total synthesis of alternaric acid reported by three groups (Ichihara & coworkers, Trost & coworkers and Johnson and Slade) which involved novel pathways for the rapid construction of this functionalized natural molecule.
