Resumen de Como interpretar una revisión sistemática con comparaciones múltiples o network metaanálisis
Gonzalo Labarca, Juan P. Uribe, Adnan Majid, Erik Folch, Sebastián Fernández Bussy
Systematic reviews evaluating multiple interventions can be useful in different clinical situations. However, some concerns arise when more than two interventions are compared and there is a paucity of good quality randomized clinical trials. A novel statistical method based on indirect comparisons, called network meta-analysis (NMA), can be a useful approach to find a clinical answer when multiple interventions are evaluated for the same outcome or comparator. The aim of this review is to describe the main characteristics and provide a user guide for a critical analysis of NMA focusing on its three main domains, namely homogeneity, transitivity and consistency.
