The Handbook of Bioethical Decisions is aimed at addressing and analyzing the most important ethical concerns and moral quandaries arisen in biomedical and scientific research. As such, it identifies and problematizes on a comprehensive range of ethical issues researchers must deal with in different critical contexts. Thus, the Handbook, Vol. I, may be helpful for them to make decisions and deliberate in complex practical scenarios. In this fashion, the volume reunites different points of view to give readers room enough to get a better knowledge and take their own position on pressing bioethical issues of the day. Consequently, this workseeks to engender dense ethical epistemology scientists can count on when conducting latest generation biomedical research. By bringing together an impressive array of contributions on the most important elements and categories for “at the bench” bioethical decisions as well as offering chapters by some of the most world renowned and prominent experts in bioethics, the Handbook, Vol. I, is a paradigmatic text in its area and a valuable resource for courses on bioethics, and biomedical research, as well as courses that discuss ethics and the biosciences at different professional levels, biomedical industry, pharmacological companies and the public sphere in general.
Introduction: Biomedical research in one world: Current and future challenges
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Bioethical decision-making about somatic cell genome editing: Sickle-cell disease as a case study
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Limits of debate: Governance of human embryo research and the making of the fourteen-day rule
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Research with human biological samples: Systematization of the phases and affected rights
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Ethical and legal considerations in genomic data sharing: Evolution of the discourse and the road ahead
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The development, implementation, and oversight of artificial intelligence in health care: Legal and ethical issues
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The use of animals in the study of human disease: Key roles of general ethical principles
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Of mice-rats and pig-men: Ethical issues in the development of human/nonhuman chimeras
A. MacKenzie-Graham
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Animal cloning: Scientific endeavour, perception and ethical debate
Andrew J. French, Alan Trounson
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Replacement, reduction and refinement: Ethical considerations in the current applications of the 3Rs
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Ethical issues in genetically modified foods: From transgenesis to CRISPR-Cas9 genome editing technology
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